Domenico Ghirlandaio. Domenico Ghirlandaio, also spelled as Ghirlandajo, was an Italian Renaissance painter born in Florence.
   Ghirlandaio was part of the so-called third generation of the Florentine Renaissance, along with Verrocchio, the Pollaiolo brothers and Sandro Botticelli. Ghirlandaio led a large and efficient workshop that included his brothers Davide Ghirlandaio and Benedetto Ghirlandaio, his brother-in-law Bastiano Mainardi from San Gimignano, and later his son Ridolfo Ghirlandaio.
   Many apprentices passed through Ghirlandaio's workshop, including the famous Michelangelo. Ghirlandaio's particular talent lay in his ability to posit depictions of contemporary life and portraits of contemporary people within the context of religious narratives, bringing him great popularity and many large commissions.
   Ghirlandaio was born Domenico di Tommaso di Currado di Doffo Bigordi. He was the eldest of six children born to Tommaso Bigordi by his first wife Antonia di ser Paolo Paoli; of these, only Domenico and his brothers and collaborators Davide and Benedetto Ghirlandaio survived childhood.
   Tommaso had two more children by his second wife, also named Antonia, whom he married in 1464. Domenico's half-sister Alessandra married the painter Bastiano Mainardi in 1494. Both Ghirlandaio's father and his uncle, Antonio, were setaiuolo a minuto. Giorgio Vasari reported that Domenico was at first apprenticed to
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