Leiden. Leiden is a city and municipality in the province of South Holland, Netherlands. The municipality of Leiden had a population of 123,856 in August 2017, but the city forms one densely connected agglomeration with its suburbs Oegstgeest, Leiderdorp, Voorschoten and Zoeterwoude with 206,647 inhabitants. The Netherlands Central Bureau of Statistics further includes Katwijk in the agglomeration which makes the total population of the Leiden urban agglomeration 270,879, and in the larger Leiden urban area also Teylingen, Noordwijk, and Noordwijkerhout are included with in total 348,868 inhabitants. Leiden is located on the Oude Rijn, at a distance of some 20 kilometres from The Hague to its south and some 40 km from Amsterdam to its north. The recreational area of the Kaag Lakes lies just to the northeast of Leiden. A university city since 1575, Leiden has been one of Europe's most prominent scientific centres for more than four centuries. Leiden is a typical university city, university buildings are scattered throughout the city and the many students from all over the world give the city a bustling, vivid and international atmosphere. Many important scientific discoveries have been made here, giving rise to Leiden's motto: City of Discoveries'. The city houses Leiden University, the oldest university of the Netherlands, and Leiden University Medical Center. Leiden University is one of Europe's top universities, with thirteen Nobel Prize winners. It is a member of the League of European Research Universities and positioned highly in all international academic rankings. It is twinned with Oxford, the location of the United Kingdom's oldest university. Leiden University and Leiden University of Applied Sciences together have around 35,000 students. Modern scientific medical research and teaching started in the early 18th century in Leiden with Boerhaave. Leiden is a city with a rich cultural heritage, not only in science, but also in the arts. One of the world's most famous painters, Rembrandt, was born and educated in Leiden. Other famous Leiden painters include Lucas van Leyden, Jan van Goyen and Jan Steen. Leiden was formed on an artificial hill at the confluence of the rivers Oude and Nieuwe Rijn. In the oldest reference to this, from circa 860, the settlement was called Leithon. The name is said to be from Germanic *leitha-canal in dative pluralis, thus meaning at the canals. Canal is actually not the completely proper word. A leitha was a human-modified natural river, partly natural, partly artificial. Leiden has in the past erroneously been associated with the Roman outpost Lugdunum Batavorum. This particular castellum was thought to be located at the Burcht of Leiden, and the city's name was thought to be derived from the Latin name Lugdunum. However the castellum was in fact closer to the town of Katwijk, whereas the Roman settlement near modern-day Leiden was called Matilo. The landlord of Leiden, situated in a stronghold on the hill, was initially subject to the Bishop of Utrecht but around 1100 the burgraves became subject to the county of Holland. This county got its name in 1101 from a domain near the stronghold: Holtland or Holland. Leiden was sacked in 1047 by Emperor Henry III. Early 13th century, Ada, Countess of Holland took refuge here when she was fighting in a civil war against her uncle, William I, Count of Holland. He besieged the stronghold and captured Ada. Leiden received city rights in 1266. In 1389, its population had grown to about 4,000 persons. In 1420, during the Hook and Cod wars, Duke John III of Bavaria along with his army marched from Gouda in the direction of Leiden in order to conquer the city since Leiden did not pay the new Count of Holland Jacqueline, Countess of Hainaut, his niece and only daughter of Count William VI of Holland. Burgrave Filips of Wassenaar and the other local noblemen of the Hook faction assumed that the duke would besiege Leiden first and send small units out to conquer the surrounding citadels. But John of Bavaria chose to attack the citadels first. He rolled the cannons along with his army but one which was too heavy went by ship.